In a randomized, double-blind, crossover study, significant symptomatic improvement was found in 10 severely affected patients, aged 3 to 21 years following 6 months of supplementation with 50 to 76 mg/kg of slow-release vitamin C.
Treated patients required 1/2 as many courses of antibiotics fo skin infections as those given placebo. Improvements in lymphocyte transformation and neutrophil chemotaxis were also seen, suggesting that vitamin C may act by boosting the immune response.
Reference: Werbach, Melvyn R., MD. “Treating Eczema with Nutrients.” Textbook of Nutritional Medicine. California, Third Line Press, 1999.